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  • How Many Calories Should I Eat While on Semaglutide? Complete Guide

How Many Calories Should I Eat While on Semaglutide? Complete Guide

Weight loss
July 13, 2025
• 6 min read
Afif
Written by
Afif
Shalu Raghav
Reviewed by:
Shalu Raghav
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How Many Calories Should I Eat While on Semaglutide? Complete Guide

Semaglutide, a medication originally developed for treating type 2 diabetes, has gained popularity as a treatment for weight loss. It’s marketed under different brand names, including Wegovy for weight loss and Ozempic for diabetes management. One of the primary ways Semaglutide works is by reducing appetite, making it easier to eat fewer calories without feeling deprived. But how many calories should you eat while on Semaglutide to ensure you get the best results?

In this detailed blog post, we will explore the ideal caloric intake for individuals taking Semaglutide, how to balance macronutrients, and tips for maintaining a healthy diet while on the medication. Whether you are using it for weight loss or managing diabetes, understanding how to manage your calories while on Semaglutide is crucial to achieving your health goals.


What is Semaglutide?

Semaglutide is a medication that belongs to a class of drugs known as GLP-1 receptor agonists. GLP-1 is a hormone in your body that helps regulate insulin secretion, glucose metabolism, and appetite. Semaglutide works by mimicking this hormone, which helps with blood sugar control in people with type 2 diabetes and reduces appetite in people trying to lose weight.

  • Wegovy is the brand name for Semaglutide when used for weight loss.
  • Ozempic is the brand name when used to treat type 2 diabetes.

Semaglutide can help individuals feel fuller after eating, which naturally leads to consuming fewer calories. It is typically taken via weekly injections, and the dosage is adjusted over time to maximize the effects.


How Many Calories Should I Eat While on Semaglutide?

When you start taking Semaglutide, your calorie needs will likely change. The appetite-suppressing effects of the drug can make it easier to eat less, but it’s important to ensure that you are still consuming enough calories to maintain good health and nutrition.

Factors That Influence Caloric Needs on Semaglutide

The number of calories you should eat while on Semaglutide depends on several factors, including:

  • Your weight loss goals: Whether you are aiming to lose weight or maintain your current weight.
  • Activity level: Whether you are sedentary, moderately active, or very active.
  • Current weight and body composition: How much muscle mass and body fat you have will influence how many calories you need.
  • Age and gender: Both age and gender play a role in determining caloric needs.

Step-by-Step Guide to Determine How Many Calories to Eat on Semaglutide

To determine how many calories you should eat while on Semaglutide, you’ll need to calculate your Total Daily Energy Expenditure (TDEE), which is the number of calories your body burns in a day. Once you have your TDEE, you can adjust your calorie intake based on your goals.

Step 1: Calculate Your Basal Metabolic Rate (BMR)

BMR represents the number of calories your body needs to perform basic life-sustaining functions like breathing, digestion, and regulating body temperature. Here’s how to calculate your BMR using the Mifflin-St Jeor equation, which is commonly used for estimating BMR.

For women:

BMR = 10 × weight (kg) + 6.25 × height (cm) – 5 × age (years) – 161

For men:

BMR = 10 × weight (kg) + 6.25 × height (cm) – 5 × age (years) + 5

Example: If you are a 30-year-old woman, weighing 160 pounds (72.5 kg), and 5’5″ (165 cm) tall:

  • BMR = 10 × 72.5 + 6.25 × 165 – 5 × 30 – 161
  • BMR = 725 + 1031.25 – 150 – 161 = 1445.25 calories/day

Step 2: Calculate Your Total Daily Energy Expenditure (TDEE)

Your TDEE accounts for the calories burned through physical activity. Depending on your activity level, you’ll need to multiply your BMR by one of the following activity factors:

  • Sedentary (little or no exercise): BMR × 1.2
  • Lightly active (light exercise or sports 1-3 days/week): BMR × 1.375
  • Moderately active (moderate exercise or sports 3-5 days/week): BMR × 1.55
  • Very active (hard exercise or sports 6-7 days a week): BMR × 1.725
  • Extra active (very hard exercise, physical job, or training twice a day): BMR × 1.9

For example, if your BMR is 1445 and you are moderately active, your TDEE would be:

TDEE = 1445 × 1.55 = 2240.75 calories/day

This means your body needs about 2241 calories per day to maintain your current weight.

Step 3: Adjust for Caloric Surplus or Deficit Based on Goals

If you are on Semaglutide for weight loss, your calorie intake should be lower than your TDEE to create a caloric deficit, which will help you lose weight. However, if you are looking to maintain your weight or gain muscle, you will adjust accordingly.

  • For weight loss: Aim for a 500-750 calorie deficit per day, which will result in about 1-1.5 pounds of weight loss per week.
  • For weight maintenance: Consume approximately the same number of calories as your TDEE.
  • For muscle gain: Aim for a 250-500 calorie surplus per day.

Example: If your TDEE is 2241 calories, and you want to lose weight, you would consume about:

  • 1491-1741 calories per day for weight loss (500-750 calorie deficit).

How Semaglutide Affects Your Appetite and Caloric Intake

One of the key ways Semaglutide helps with weight loss is by reducing appetite. Here’s how:

1. Appetite Suppression

Semaglutide mimics a hormone in your body that signals fullness to the brain, helping you feel satisfied with smaller portions. As a result, you may naturally eat fewer calories without feeling deprived.

2. Increased Satiety

Not only does Semaglutide make you feel less hungry, but it also enhances feelings of fullness after meals. This can make it easier to stick to your calorie goals without constantly battling cravings.

3. Calorie Reduction

With the appetite-suppressing effects of Semaglutide, many people find that they are naturally eating fewer calories even without making drastic changes to their diet. This is because your body may no longer crave or feel the need to eat as much food as it did before starting the medication.


What Foods Should You Focus On While on Semaglutide?

While Semaglutide helps reduce appetite, it’s still important to focus on nutritious foods that provide your body with the essential vitamins, minerals, and macronutrients it needs to function properly. Here are some food categories to include in your diet:

1. Protein-Rich Foods

Protein is essential for muscle growth, repair, and overall health. Aim for about 20-30% of your calories from protein.

  • Chicken, turkey, fish, eggs, tofu, and beans.

2. Healthy Fats

Healthy fats help with hormone production, brain function, and overall cell health. Aim for about 20-35% of your calories from healthy fats.

  • Avocados, nuts, seeds, olive oil, and fatty fish.

3. Fiber-Rich Carbohydrates

Since Semaglutide can slow down the emptying of your stomach, it’s important to focus on fiber to keep your digestive system working efficiently. Include whole grains, vegetables, and fruits in your diet.

  • Oats, quinoa, sweet potatoes, leafy greens, and berries.

How to Track Your Calories Effectively on Semaglutide

Accurately tracking your calories can help ensure that you’re staying within the right range for your goals. Here are some tips:

1. Use a Calorie-Tracking App

Apps like MyFitnessPal, Lose It!, or Cronometer can help you log your food and track your calorie intake. These apps are user-friendly and offer a large database of foods.

2. Measure Your Portions

To get an accurate picture of how much you’re eating, measure your portions. You can use a kitchen scale or measuring cups to ensure you’re eating the right amount of each food.

3. Adjust as Needed

If you’re not seeing the weight loss or muscle gain you expect, adjust your calorie intake. If you’re losing weight too slowly, try adding more protein or slightly increasing your calories. If you’re gaining fat, reduce your calorie intake slightly.


FAQ: How Many Calories Should I Eat While on Semaglutide?

1. How many calories should I eat on Semaglutide?

While on Semaglutide, aim for a caloric deficit (if you’re trying to lose weight) or maintenance based on your TDEE. A common range for weight loss is 1,200-1,500 calories per day for women, and 1,500-1,800 calories per day for men, depending on activity level.

2. Will I feel hungry on Semaglutide?

Semaglutide reduces appetite by mimicking a natural hormone that signals fullness to the brain. Many people experience less hunger and increased satiety while using it.

3. How does Semaglutide help with weight loss?

Semaglutide helps with weight loss by reducing appetite, leading to caloric intake reduction. This makes it easier to stick to a calorie-controlled diet for weight loss.

4. What foods should I eat while on Semaglutide?

Focus on high-protein foods, healthy fats, and fiber-rich carbohydrates to ensure you’re getting the nutrients your body needs while losing weight.

5. Can I still eat my favorite foods on Semaglutide?

While Semaglutide helps reduce appetite, it’s important to focus on nutrient-dense foods for better health and long-term weight management. Indulge occasionally but be mindful of portion sizes and overall calorie intake.


Conclusion

When on Semaglutide, managing your caloric intake is crucial for achieving your weight loss goals. The medication helps reduce appetite, making it easier to eat fewer calories, but it’s still important to focus on consuming enough protein, healthy fats, and fiber-rich carbs to ensure your body gets the nutrients it needs.

By calculating your TDEE, maintaining a caloric deficit, and choosing nutrient-dense foods, you can optimize your results while on Semaglutide. Always listen to your body and adjust your calorie intake as needed for the best results.

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